The virtual course "Whole genome sequencing of bacterial genomes: tools and applications - Virtual Course - Coursera", is a course with different contents and that offers video classes of Approx. 7 hours to complete. Explore its essential features, and click the orange button to get detailed information on the Coursera e-Learning platform
This course will cover the topic of Whole Genome Sequencing (WGS) of bacterial genomes, which is becoming increasingly relevant to the medical sector.
WGS technology and applications are high on the international political agenda as classical methods are being replaced by WGS technology and therefore bioinformatics tools are extremely important to enable people working in this sector can analyze the data and obtain results that can be interpreted.
and is used for different purposes.
The course will provide students with a foundation to understand and become familiar with WGS applications in bacterial surveillance, including species identification, typing and characterization of antimicrobial resistance and virulence traits, as well as plasmid characterization.
It will also give students the opportunity to learn about the online tools and what they can be used for through demonstrations on how to use some of these tools and exercises for students to solve using freely available WGS analysis tools.
At the end of this course, you should be able to: 1.
Describe the general principles in the typing of bacteria 2.
Give examples of the applications of whole genome sequencing for surveillance of bacterial pathogens and antimicrobial resistance 3.
Apply genomic tools for subtyping and surveillance 4.
Define the concept of next-generation sequencing and describe NGS 5 sequencing data.
Describe how to do a de novo assembly from raw reads to contigs 6.
List the methods behind the tools for species identification, MLST typing, and resistance gene detection 7.
Apply the tools for species identification, MLST typing and detection of resistance genes in real cases of other bacterial and pathogen genomes.
8.
Describe the methods behind the typing tools for Salmonella and E.
coli, plasmid replicon detection and plasmid typing 9.
Use the tools for typing Salmonella and E.
coli, plasmid replicon detection, and plasmid typing in real cases from other bacterial and pathogen genomes.
10.
Explain the concept and be able to use the integrated bacterial analysis pipeline for batch analysis and typing of genomic data 11.
Demonstrate how to build a phylogenetic tree based on SNP 12.
Apply the phylogenetic tool to build phylogenetic trees and explain the relationship of bacteria or pathogenic strains 13.
Describe how to create your own sequence database 14.
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Technical University of Denmark (DTU)
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